3Rs Search Hedges 사례

원하는 연구 주제의 완성된 검색식 뒤에 아래의 Search Hedge를 추가하여 3Rs 검색을 수행할 수 있다.

PubMed

• Selected Animal Search Hedges
  • 링크를 클릭하여 파일을 다운로드 받은 후, 파일 내용을 참고하여 다양한 동물 종 검색식을 활용할 수 있다.
  • Search hedges developed by the Search Strategies Working Group of the Animal and Veterinary Information Specialists caucus (MLA) for retrieving citations on animals commonly used in research.
• Alternative Methods of Genotyping Mice Hedges
  • AND (“Mice”[MeSH Major Topic] OR “Rats”[MeSH Major Topic] OR “Rodentia”[MeSH Major Topic] OR mouse[Title/Abstract] OR mice[Title/Abstract] OR mus[Title/Abstract] OR murine[Title/Abstract] OR rat[Title/Abstract] OR rats[Title/Abstract] OR rattus[Title/Abstract] OR R-norvegicus[Title/Abstract] OR rodent*[Title/Abstract]) AND (“Genotyping Techniques”[Mesh Major Topic] OR genotyping[Title] OR (genotyping[Title] AND (Technique*[Title] OR method*[Title])) OR (DNA[Title] AND (sampl*[Title] OR collect*[Title]))) AND (“Animal Use Alternatives”[MeSH Terms] OR “Animal Welfare”[Mesh Terms] OR noninvasive[Title/Abstract] OR non-invasive[Title/Abstract] OR minimallyinvasive[Title/Abstract] OR less-invasive[Title/Abstract] OR less-aversive[Title/Abstract] OR non-aversive[Title/Abstract] OR welfare[Title/Abstract] OR well-being[Title/Abstract] OR wellbeing[Title/Abstract] OR stress*[Title/Abstract] OR refine*[Title/Abstract] OR distress*[Title/Abstract] OR 3Rs[Title/Abstract] OR three-rs[Title/Abstract] OR animal-usealternative*[Title/Abstract] OR alternative*[Title/Abstract] OR humane[Title/Abstract] OR pain*[Title/Abstract] OR anxiety[Title/Abstract] OR best-method*[Title/Abstract] OR bestpractice*[Title/Abstract] OR preferred-method*[Title/Abstract] OR recommend*[Title/Abstract] OR guideline*[Title/Abstract])
• Alternatives to Oral Gavage in Mice and Rats
  • AND (Mice[majr] OR Rats[majr] OR Rodentia[majr] OR “mus musculus”[ti] OR “m musculus”[ti] OR mouse[ti] OR mice[ti] OR murine[ti] OR rat[ti] OR rats[ti] OR rattus[ti] OR “rattus norvegicus”[ti] OR “r norvegicus”[ti] OR “rodent”[ti] OR “rodents”[ti]) AND (voluntary[tiab] OR “self administration”[tiab] OR Self Administration[mh] OR “voluntary ingestion”[tiab:~3] OR “voluntary ingest”[tiab:~3] OR “voluntary ingests”[tiab:~3] OR “voluntarily ingest”[tiab:~3] OR “voluntarily ingests”[tiab:~3] OR “voluntarily ingested”[tiab:~3] OR “voluntary dosing”[tiab:~4] OR “voluntary oral”[tiab:~4] OR “oral dosing”[tiab] OR “voluntary consumption”[tiab:~3] OR “oral infection”[tiab] OR “syringe feeding”[tiab] OR Drinking Water[mh] OR Drug Delivery Systems[mh] OR Food, Formulated[mh] OR Pharmaceutical Preparations/methods[MeSH]) AND (Animal use alternatives[mh] OR Animal Welfare[mh] OR 3rs[tiab] OR “three rs”[tiab] OR welfare[tiab] OR “well being”[tiab] OR wellbeing[tiab] OR gavag*[tiab] OR mortality[tiab] OR morbidit*[tiab] OR “adverse effects”[tiab] OR “acute stress”[tiab] OR anxious[tiab] OR “less invasive”[tiab] OR welfare[tiab] OR “less aversive”[tiab] OR “non aversive”[tiab] OR nonaversive[tiab] OR “less aversive”[tiab] OR “less stressful”[tiab] OR “less stressful alternative”[tiab] OR “minimally invasive”[tiab] OR painful[tiab] OR pain[tiab] OR distress[tiab] OR “low stress”[tiab] OR “non invasive”[tiab] OR noninvasive[tiab] OR palatable[tiab] OR “stress-free”[tiab]) AND (Gelatin/administration and dosage[MeSH] OR Drinking Water[mh] OR “drinking water”[tiab] OR lixit[tiab] OR “water bottle”[tiab] OR bread[tiab] OR cookie*[tiab] OR micropipette[tiab] OR microcapsul*[tiab] OR gelatin[tiab] OR jelly[tiab] OR jam[tiab] OR dough[tiab] OR paste[tiab] OR wafer*[tiab] OR “peanut butter”[tiab] OR Nutella[tiab] OR “chocolate milk”[tiab] OR “condensed milk”[tiab] OR juice[tiab] OR jello[tiab] OR syrup[tiab] OR paste[tiab] OR mealworm*[tiab] OR palatable[tiab] OR refinement[tiab] OR “tablet formulation”[tiab] OR “gel delivery system”[tiab] OR “drinking water”[tiab] OR palatable[tiab] OR treat*[tiab] OR liquid*[tiab] OR suspension[tiab] OR sweet[tiab] OR flavored[tiab] OR flavoured[tiab]) NOT (Binge-Eating Disorder[mh] OR Craving[mh] OR Food Addiction[mh] OR Bulimia[mh] OR Alcoholism[mh] OR Behavior, Addictive[mh] OR Addiction Medicine[mh] OR Cocaine[mh] OR addiction[tiab] OR addictive[tiab])
• To replacement
  • AND ((“Computer Simulation”[Mesh] OR simulation[tiab] OR “Cadaver”[Mesh] OR cadaver[tiab] OR “Culture Techniques”[Mesh] OR “Cells, Cultured”[Mesh] OR “cultured cells”[tiab] OR “cell culture”[tiab] OR “cell cultures”[tiab] OR vitro[tiab] OR “Models, Theoretical”[Mesh] OR model[tiab] OR models[tiab] OR modeling[tiab] OR modelling[tiab] OR “Manikins”[Mesh] OR manikin[tiab] OR manikins[tiab] OR mannequin[tiab] OR mannequins[tiab])) AND ((“Imaging, Three-Dimensional”[Mesh] OR three-dimensional[tiab] OR 3D[tiab] OR 3-D[tiab]) AND (image[tiab] OR images[tiab] OR imaging[tiab]))
• Reduction & Refinement
  • AND (“Pain”[Mesh] OR “Pain Management”[Mesh] OR “Anesthesia and Analgesia”[Mesh] OR  “Analgesics”[Mesh] OR “Analgesics”[Pharmacological Action] OR “Anesthetics”[Mesh] OR  “Anesthetics”[Pharmacological Action] OR “Animal Welfare”[Mesh] OR “Animal Use Alternatives”[Mesh] OR “Stress, Psychological”[Mesh] OR “Stress, Physiological”[Mesh] OR stress[tiab] OR distress[tiab] OR pain*[tiab] OR analgesia[tiab] OR analgesic*[tiab] OR anesthesia*[tiab] OR anesthetic*[tiab] OR welfare[tiab] OR alternative*[tiab] OR “Disease Models, Animal”[mesh] OR “animal model”[tiab])
• To exclude animals and humans
  • NOT (“Animals”[Mesh] OR “Humans”[Mesh])
• To include possible non-animal models/methods
  • AND ((“Models, Theoretical”[Mesh] NOT “Disease Models, Animal”[Mesh]) OR “Computer Simulation”[Mesh] OR “Cadaver”[Mesh] OR “Culture Techniques”[Mesh] OR “Cells, Cultured”[Mesh] OR “In Vitro “[Publication Type])
• To exclude mammals
  • AND “Animals” [Mesh] NOT “Mammals”[Mesh]

Web of Science

• Alternative Methods of Genotyping Mice Hedges
  • (TI=(mouse OR mice OR mus OR murine OR rodent* OR rat OR rats OR rattus OR R-norvegicus) OR AB=(mouse OR mice OR mus OR murine OR rodent* OR rat OR rats OR rattus OR R-norvegicus)) AND (TI=(genotyping OR (genotyping AND (technique* OR method)) OR (DNA AND (sampl OR collect)))) AND (TI=(noninvasive OR non-invasive OR minimally-invasive OR less-invasive OR less-aversive OR non-aversive OR welfare OR well-being OR wellbeing OR stress OR refine* OR distress* OR 3Rs OR three-rs OR animal-use-alternative* OR alternative* OR humane OR pain* OR anxiety OR best-method* OR best-practice* OR preferred-method* OR recommend* OR guideline) OR AB=(noninvasive OR non-invasive OR minimally-invasive OR less-invasive OR less-aversive OR non-aversive OR welfare OR well-being OR stress OR refine* OR distress* OR 3Rs OR three-rs OR animal-use-alternative* OR alternative* OR OR pain* OR anxiety OR best-method* OR best-practice* OR preferred-method* OR recommend* OR guideline*))
• Alternatives to Oral Gavage in Mice and Rats
  • AND (((TS=((Gavage NEAR/5 (alternative* OR refinement)) OR ((voluntary OR voluntarily) NEAR/3 (ingest* OR oral* OR intake OR method* OR technique* OR administration OR administer* OR dose OR dosing)) OR “syringe feeding” OR “oral infection”)) AND TS=(“adverse effect*” OR “animal welfare” OR anxiety OR anxious OR humane OR “less invasive” OR “less aversive” OR “non invasive” OR noninvasive OR “reduce stress” OR “stressfree” OR “non aversive” OR “less aversive” OR “less stressful” OR voluntary OR 3Rs OR “Three Rs” OR “animal use alternatives”)) AND TI=(mice OR rat OR rats OR rodent* OR murine OR “Mus musculus” OR “M musculus” OR rattus OR “Rattus norvegicus” OR “R norvegicus”)) AND TS=(bread OR “bread feeding” OR dough OR gelatin OR gel OR jelly OR cookie OR wafer* OR pellet* OR “peanut butter” OR Nutella OR “chocolate milk” OR “condensed milk” OR juice OR jello OR syrup OR paste OR jam OR mealworm* OR micropipette OR refinement* OR “tablet formulation” OR “Medicated Dosing System” OR “medicated diet” OR “alternative dosing method” OR “Bio Serv” OR bioserv OR microcapsul* OR flavo$red OR “drinking water” OR palatable OR palatability OR treat OR treats OR liquid)