Contents
Editorial 249
Spotlight on Three Rs Progress 251
Resources Round-up 253
50th Anniversary Article
The Evolution of Regulatory Toxicology: Where is the Gardener? 255
Robert Landsiedel, Barbara Birk and Dorothee Funk-Weyer
2021 Michael Balls Award 263
Review Articles
The Use of Human Tissues for Research: What Investigators Need to Know 265
Marianna J. Bledsoe and William E. Grizzle
Biobank Personnel — The Key to its Success 275
Anna Chróscicka, Angelika Paluch, Ilona Kalaszczy ´ nska and Ilona Szab ´ łowska-Gadomska
Research Article
Development of an Accessible Gene Expression Bioinformatics Pipeline to Study Driver Mutations of
Colorectal Cancer
282
Lisa van den Driest, Caroline H. Johnson, Nicholas J.W. Rattray and Zahra Rattray
Workshop Report
Ciliary Beat Frequency: Proceedings and Recommendations from a Multi-laboratory Ring Trial Using 3-D
Reconstituted Human Airway Epithelium to Model Mucociliary Clearance 293
Holger P. Behrsing, Adam Wahab, Lindsey Ukishima, Chad Grodi, Stefan Frentzel, Stephanie Johne, Shinkichi Ishikawa, Shigeaki Ito,
Roman Wieczorek, Jessica Budde, Brian M. Keyser, Linsey E. Haswell, David Thorne, Emma Bishop, Damien Breheny, Xuefei Cao,
Qin Qin and Vivek Patel
Conference Diary 310