Contents
Editorial 315
Spotlight on Three Rs Progress 317
Resources Round-up 320
50th Anniversary Article
A History of Regulatory Animal Testing: What Can We Learn? 322
Doortje Swaters, Anne van Veen, Wim van Meurs, Janette Ellen Turner and Merel Ritskes-Hoitinga
Review Article
Case Studies Exemplifying the Transition to Animal Component-free Cell Culture 330
Tilo Weber, Joachim Wiest, Stina Oredsson and Karen Bieback
Research Articles
An Evaluation of Different Types of Peptone as Partial Substitutes for Animal-derived Serum in Vero
Cell Culture 339
Chloe Lezin, Philippe Mauduit, Georges Uzan and Mohamed Essameldin Abdelgawad
Transparency in Non-Technical Project Summaries to Promote the Three Rs in Respiratory Disease Research 349
Martina Bonassera, Esther Clews and Kelly BeruB ´ e´
Comment
Addressing Animal Welfare Issues in Fetal Blood Collection for Fetal Bovine Serum Production 365
Terence J. McCann and Carol Treasure
Conference Diary 369