Contents
Editorial 155
Spotlight on Three Rs Progress 157
Resources Round-up 159
Review Article 161
The Application of New Approach Methodologies in Respiratory Disease Research: Their Role in Improving
Translational Medicine from Bench to Bedside
Artur C.G. da Silva and Marize C. Valadares
Research Articles 175
Use of the Allium cepa Model to Assess the Cytogenotoxicity of Luffariella herdmani Marine Sponge Extract
Sashini U. Kuruppuarachchi, Uthpala A. Jayawardena and Varuni K. Gunathilake
A Human Cell-based Assay to Assess the Induction of Vasculature Formation for Non-genotoxic
Carcinogenicity Testing Purposes: A Pilot Study
Veera Hautanen, Tarja Toimela, Martin Paparella and Tuula Heinonen
In Silico Prediction of Eye Irritation Using Hansen Solubility Parameters and Predicted pKa Values
Martin Andersson, Ulf Norinder, Swapnil Chavan and Ian Cotgreave
Conference Diary 210