Table of contents 1DRUG DEVELOPMENT 17From mouse to 30Toxicity of lipsticks? 44Safety measures 54METHODOLOGY DEVELOPMENTS 61Experiments on the organs of dead animals 68Human surgical and postmortem material 75The lonely heart 117Safety for the healthy treatment for the sick 128A bridgehead… 더 보기 »Scientific Alternatives to Animal Experiments
An expert report by : DR Hadwen Trust / FRAME / St Andrew Animal Fund IntroductionThere have been many reports on the subject of experiments on non-human primates,mirroring the level of concern about this issue. Why another report now?An… 더 보기 »Replacing Primates in Medical Research
Training materials and resources CONTENTSPrefaceCan the use of animals in scientific research be justified?Discussion seminar for teaching animal ethics/law to students who use isolated tissuesin their studiesScience and Society: Can the use of animals in research be justified?A debate… 더 보기 »Animal Welfare, Ethics and te 3Rs
Good Search Practive on Animal Alternaives How best to search information on the 3Rs (replacement, reduction, refinement of animal use) in the WWWMaking full use of all sources of information on alternative methods is a key part of… 더 보기 »The Eurl Ecvam Search Guide
Refinement. Reduction. Replacement Over 75 contributors from industry, academia, and government evaluate the latest developments and possible directions in alternatives to using animals in research and testing, and explain the regulatory climate that surrounds the controversial topic. Among the… 더 보기 »Animal Test Alternatives
In Vitro Toxicology : Tenth Anniversary Symposium of CAAT Part One: Symposium Presentations In Vitro Approaches to NeurotoxicityCholinergic Cell Lines as Models for Testing Drug Efficacy and ToxicityJ.K. Blusztajin, A. Venturini, D.A. Jackson, U. Schuler, H.J. Lee, and… 더 보기 »Alternative Methods In Toxicology 9
In Vitro Toxicology : Mechanisms and New Technology Part One: Symposium Presentations Mechanisms of Tissue InjuryArachidonic Acid Metabolites and Phagocytic Cells as Mediators of Tissue InjuryH.J. Forman and T.W. RobisonMolecular Studies of n-Hexane and Carbon Disulfide NeuropathiesD.G. Graham,… 더 보기 »Alternative Methods In Toxicology 8
In Vitro Toxicology : New Directions Part One: Sympopsium Presentations Use of In Vitro Methods in Product DevelopmentIn Vitro Approaches to Drug DiscoveryUse of In Vitro Assays to Define the Malignant Activities of Tumor Cells and to Screen… 더 보기 »Alternative Methods In Toxicology 7
Progress In In Vitro Toxicology Part One: Sympopsium Presentations Epidermal ToxicitySkin ToxicityL.A. GoldsmithProteinase Biology in Keratinocyte Culture: Possible Utility as a Model for Toxicological TestingG.S. LazarusTestskin: A Hybrid Organism Covered by a Living Human Skin Equivalent DEsigned for Toxicity… 더 보기 »Alternative Methods In Toxicology 6
A Critical Evaluation of Alternatives To Acute Ocular Irritation Testing Summary and RecommendationsHistorical Perspective on Eye Irritation TestingCurrent In Vivo Testing Protocols, Procedures, and PracticesAdequacy of Current In Vivo MethodsPotential Approaches for the Development of In Vitro Alternatives to… 더 보기 »Alternative Methods In Toxicology 4